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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Does this blood Test Result Mean?

Hello~

I am HOPING that you could give me your opinion/interpretation based on the following lab results. Your help is GREATLY appreciated!!

Serum protein Immunofixation: normal; no monoclonal Ig
IgG: low at 314
IgA: low at 42
IgM: wnl = 79
CBC, Chem Panel, ESR, LDH: WNL w/the following exceptions...
Globulin: low = 2.0
Gamma globulin: 0.4
A/G Ratio: high = 2.3
Creatinine: 1.09
GFR: 53

Hx: 49 yo. white female; hx of NHL in remission; dx'd w/ hypogammaglobulinemia 2007; diabetes - type II; Hashimoto's thyroiditis; anti-cardiolipin antibodies and anti-phospholipid antibody syndrome w/ 3 DVTs; osteoporosis; recurrent URIs.

THANK YOU so very much for expert opinion and assistance!!
posted on Thu, 13 Mar 2014
Twitter Mon, 2 Mar 2015 Answered on
Twitter Tue, 3 Mar 2015 Last reviewed on
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Pathologist and Microbiologist,  's  Response
Hi! after analysing the report results, I could summarize and opine that:

1. there is no residual disease or evidence of NHL; Remission status being maintained!

2. hypogammaglobulinemia and overall low globulin levels could be due to reduction in the number of B-cells due to therapy and related kidney damage as GFR is reduced!

3. I think low globulin level is good for your thrombotic tendencies; therefore I think this condition as favorable to your health!

Keep in touch with your primary doctor and have an open discussion also or revert back to me if any more explanation is required!

regards!
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What Does this blood Test Result Mean?

Hi! after analysing the report results, I could summarize and opine that: 1. there is no residual disease or evidence of NHL; Remission status being maintained! 2. hypogammaglobulinemia and overall low globulin levels could be due to reduction in the number of B-cells due to therapy and related kidney damage as GFR is reduced! 3. I think low globulin level is good for your thrombotic tendencies; therefore I think this condition as favorable to your health! Keep in touch with your primary doctor and have an open discussion also or revert back to me if any more explanation is required! regards!